The paper introduces the overall design of national level medical information health platform during the "13th Five Year Plan" and function of medical institution informatization in promoting the management for infectious disease report, and analyzes the problems and challenges faced by direct report of infectious diseases on the Internet. China is suggested to release the data exchange work and technology scheme together with the Specification for Infectious Diseases Information Report Management that is newly issued in 2015, in order to guide the medical institutions or population health information platform to achieve automatic data exchange with the infectious disease network direct report system.