The paper analyzes the literatures relevant to Alzheimer Disease(AD) included in PubMed and the China National Knowledge Internet (CNKI) by the methods of co-word matrix, clustering analysis and other data statistical methods, analyzes and explores the study status of this field from the aspects of overseas and domestic research focuses, important authors and their cooperative networks, countries and regions, and proposes China to focus on the research of pathogenesis and therapeutic schemes of AD in accordance with the situation of population aging and strengthen cooperation with foreign experts and scholars of relevant fields.