The paper elaborates the design of food safety risk monitoring information platform system, including the business framework, application system, standards and regulations system, data collection and exchange method, foodborne disease early warning based on big data and other aspects, points out that the building of the platform is conducive to improving the data collection and exchange capacity of the national and provincial platforms, promoting the informatization building of food safety in various regions, and perfecting the work process of national food safety risk monitoring and management.