Purpose/Significance To explore the health information service framework based on artificial intelligence (AI), and to provide a theoretical basis for the health information service of medical libraries. Method/Process By using the literature analysis method, the current situation of health information services in libraries is sorted out, the existing problems of health information services in medical libraries are analyzed, and a five-stage service framework with AI as the core is constructed. Result/Conclusion In the process of providing health information services, medical libraries are confronted with problems such as information collection, service models, and team building. The health information service framework based on AI can provide theoretical references and practical paths for the innovative transformation of services.