Purpose/Significance To design an agent scheme that integrates domain knowledge bases and user characteristics, so as to enhance the accuracy of network health information assessment and the effectiveness of decision support. Method/Process A knowledge base in the medical field is constructed. By integrating methods such as retrieval enhancement and so on, a closed-loop assessment process of “multimodal analysis,knowledge enhancement retrieval, four-dimensional evaluation model(trustworthy interpretation, risk warning, evidence citation, personalized suggestions)” is realized. Result/Conclusion This framework can enhance the readability of health information and assist in supporting information-based decision-making. The adoption of evidence-based content risk assessment methods is conducive to the improvement of public health information literacy.