Purpose/Significance To develop a collaborative remote consultation system based on 5G and augmented reality (AR) smart glasses, so as to provide practical references for enhancing the diagnostic and treatment capabilities of grassroots oncology practitioners and optimizing regional healthcare resource allocation. Method/Process Six member units from the medical alliance of the Second Affiliated Hospital of Hainan Medical University are selected. A retrospective non-randomized controlled trial design is employed. 40 remote oncology consultation cases are divided into an intervention group (AR+5G consultation, n=20) and a control group (traditional video consultation, n=20). The differences between the two groups are compared and analyzed in terms of consultation efficiency, clinical diagnostic effectiveness, and expert satisfaction. Result/Conclusion Compared to traditional video consultation, the AR+5G consultation system demonstrates significant advantages in terms of technical performance, process efficiency, and clinical efficacy.