Using the Prescription Automatic Screening System (PASS) as the foundation and core, the Hospital Management Information System (HIS), Electronic Medical Record (EMR) and Laboratory Information Management System (LIS) as the main informatization means, all of the above provide effective data analysis and support services to clinical rational medication, offer an objective basis to medical management and decision-making. The rational clinical medication management system is thus composed. Moreover, the rationality of medication will be well improved.