The paper discusses constructing a platform for multi-source information collection and digital image feature analysis for osseous tumor using database technology, carrying out integrated management of multi-source patients’ information, extracting digital features of osseous tumor image information. The result shows that the latter one has significance for identifying lesions and normal tissues. The system is propitious to efficiency of series of medical activities such as case retrieval, statistical analysis, follow-up visit and evaluations, in the meanwhile provides support platform for osseous tumor automatic identification and diagnosis.