Through simulation testing, questionnaire and interviewing， the paper evaluates the user experience of three major types to Chinese Center for Disease Control and Prevention website. It analyzes the results from the first impression, mission execution situation and post feedback, clarifies the existing problems of the website and proposes strategies for improving the website, including strengthening popularization, beautifying the homepage, reinforcing website planning, promoting usability and interaction and so on, so as to improve service level and effects of the website.