Important National Science & Technology Specific Projects，"the significant formulation of new drugs"，"the prevention and control of major infectious diseases such as AIDS and viral hepatitis", need a stronger support of medical information services. The paper analyzes the information demand characteristics of the Important National Science & Technology Specific Projects, combined with information service advantages of the Library of Chinese Academy of Medical Sciences in document delivery,sci-tech novelty assessment,intelligence analysis,subject services and personnel，it initially construct information service framework in Library of Chinese Academy of Medical Sciences orienting to the Important National Science & Technology Specific Projects,proposes information service strategies from 4 aspects:information service mode,means,contents and personnels.