The paper divides the students into study group and contrast group, the combined mode of Problem-based Learning (PBL) teaching method and traditional teaching method (LBL) is carried out in study group, while traditional LBL teaching method is used in contract group, then the computer skills training is carried out in hospital. Examination results and scores of questionnaire are compared between two groups. It shows that average scores of theory examination and operation examination, as well as the average scores of questionnaire items in study group are higher than that of contract group, which proves that PBL teaching method has more advantages than traditional teaching method.