Based on literature research, the paper builds a sci-tech influence evaluation index system for hospitals with the Delphi method and ranks the sci-tech influence of 60 hospitals in terms of expertise. By using radial basis function neural network and taking 50 hospitals as training samples and 10 hospitals as test samples, it builds a sci-tech influence evaluation model for the hospitals based on the radial basis function. As indicated by experimental results, this evaluation model fits thoughts of experts well and evaluates the sci-tech influence of hospitals truly and effectively.