Based on Delphi method, the paper investigates several key problems about the application of reading therapy in clinical nursing, including the prospect, necessity, advantages, obstacles, practice pattern, etc. The result shows that the reading therapy meets the development trend of modern medicine. The paper analyzes the advantages and obstacles of applying reading therapy in clinical nursing, and puts forward some countermeasures such as establishing the multi-cooperation system, cultivating reading therapy experts, developing pilot bases, and strengthening publicity,etc..