The paper analyzes the potential safety hazards of infusion work of the hospital, introduces the hardware environment, business process and topological structure of the mobile infusion system, puts forward the solution to the mobile infusion system based on intelligent terminal PDA, Wireless Local Area Network(WLAN) and barcode recognition, and optimizes the system according to the utilization condition, in order to improve the operating efficiency in the meantime of eliminating the potential safety hazards of infusion.