On the basis of summarizing association rules algorithm and algorithm optimization, the paper explores the rules of prescription compatibility in the scheme for apoplexy diagnosis and treatment through Traditional Chinese Medicine(TCM), establishes the TCM Electronic Medical Records(EMR) database, processes and analyzes the data based on the classical association rule-Apriori algorithm, introduces the parameter optimization mining results of correlated measurement parameters Kulc and IR, eliminates pseudo strong association principle, gets the drug compatibility with strong correlation and theoretical significance, and provides theoretical guidance and reference for apoplexy medication through TCM.