The paper elaborates on the development history and the status quo of specialty of medical information engineering. By taking Yunnan University of Traditional Chinese Medicine(TCM) as an example, it introduces the background, cultivation objectives and knowledge system building of the specialty of medical information engineering, and analyzes the employment direction and prospects of the graduates of the specialty in universities and colleges of TCM, which includes further study, engaging in related work in government, public institutions, and enterprises as well as self-employment, etc.