Based on such multi-source data as papers, patents, drug discoveries, and clinical experiments, the paper analyzes the development trends, study themes, priority medicines, and serious diseases of Hematopoietic Stem Cell (HSC) in the period from 2009 to 2018 by bibliometric analysis, text mining, visualization and other methods. It summarizes the clinical study application hotspots of HSC, which serves as reference for clinical decision making and the management of science and technology.