The paper analyzes user characteristics and functional requirements, expounds the design and implementation of the osteoporosis(OP) prevention and treatment system based on mobile devices from the aspects including main idea, architecture, workflow, functions, etc., points out that the system provides convenient self-testing tools for patients and complete patient information management for doctors, and provides community health service centers with comprehensive whole-process management for the family doctor contract signing and implementation, which is helpful to improve the efficiency of OP prevention and treatment.