A system dynamics model for the dissemination of pseudo-health information in public health emergencies is built based on the SIRS model, and the dissemination process and influencing factors of pseudo-health information in network space is analyzed. The results show that the number of susceptible population, the level of public health emergencies, health information literacy, relationship strength, government credibility and other influencing factors play key roles in the dissemination of pseudo-health information in public health emergencies, and then the corresponding suggestions on governance are put forward.