The paper introduces the research status of library space reengineering and service transformation at home and abroad, takes the library of the First Affiliated Hospital of Chongqing Medical University as an example, expounds the path of library space reengineering and the integration of space reengineering and service transformation, summarizes practical experience, including paying attention to top-level design, laying a solid foundation for development and optimizing user experience, and provides references for related study.