Based on the information of scientific research strategic planning, research projects and funded scientific research projects published by the United States National Library of Medicine (NLM) in the past five years, the research layout trend, characteristics and experience of NLM under the background of data-driven are studied and evaluated from the perspectives of research implementation mechanism, investment, funding type, funding institution and funding focus by comprehensively using bibliometric analysis tools such as statistical analysis and cluster analysis, so as to provide references for scientific research planning and decision-making of medical library and medical information science in China.