Purpose/Significance To summarize the status quo and trend of the development of intelligent medicine driven by data and model, so as to improve the level of clinical medicine and promote the development and application of intelligent medicine.Method/Process The paper introduces the background of the emergence of intelligent medicine, and expounds the impact of big data integration and drive, artificial intelligence (AI), metaverse medical care, innovative talents of medicine and engineering integration on the development of intelligent medicine as well as specific application. Result/Conclusion Intelligent medicine is one of the future development directions of medicine, and its development depends on the big data computing power and the construction of storage platform, the construction of health and medical big data standards and norms, medical AI technology, the construction of ethics and regulations related to intelligent medicine, the construction of interdisciplinary talent team, etc.