Purpose/Significance To solve the problem of relatively centralized and unbalanced distribution of high-quality medical resources in the process of continuously deepening the reform of the medical and health system,and to propose a new industry cloud solution and architecture for medical alliance. Method/Process The paper builds an open and integrated cloud platform, develops a cloud application supermarket and a unified interactive service platform, and promotes these applications in the pilot area of Chengdu. Result/Conclusion By developing and applying the medical cloud platform, information interconnection between the medical alliance of Chengdu Third People’s Hospital and other eight medical institutions can be realized. The medical information barriers between medical alliance can be broken up, the service provision within medical alliance can be effectively promoted, and the innovation of the city’s medical industry can be promoted.