Purpose/Significance Exploring data governance models and method paths in response to the growing demand for collaborative management of data across multiple institutions. Method/Process Thoroughly analyze the main problems in the integration and use of medical data in multiple hospital areas. Based on the current management mode, information construction, technical architecture, and other aspects of each hospital area, different models and methods are adopted for governance of retrospective and prospective data. Result/Conclusion The data standards for multiple hospital districts are unified, and the data sharing rate and usage efficiency are significantly improved. The data quality of the multi-hospital district business system is continuously improved, and the cross hospital interval data security guarantee mechanism is improved.