Purpose/Significance To build a mobile payment platform based on outpatient prescription payment, and to provide technical references for online mobile payment of primary medical institutions. Method/Process The mobile payment platform based on outpatient prescription payment is designed and constructed from four aspects:system architecture, network architecture, business process and platform docking. Result/Conclusion The mobile payment platform has been put into use successfully.The usage rate of mobile payment method in relevant departments reaches 66%, and the application effect is good, which can provide references for other primary institutions.