Purpose/Significance The large generative language model (GLM) represented by ChatGPT has driven the rapid development of artificial general intelligence technology. Weather GLM can be successfully used in medical applications is a closely medical treatment issue in both academia and industry. The paper aims to delve into the opportunities and challenges of GLM in the application of medical treatment in China. Method/Process Starting from three aspects:knowledge container, capability engine, and autonomous agent, the paper analyzes the new opportunities of GLM in improving medical quality and efficiency, solving the imbalance problem of medical development in China, intelligent management and decision-making of chronic diseases, coping with population aging, and accelerating medical research. At the same time, it points out the limitations of the application of large models in the medical field. Result/Conclusion The big model driven approach is expected to become a new paradigm for intelligent healthcare. In response to the shortcomings of large models in medical applications, specific suggestions are proposed.