Purpose/Significance To analyze the application of persuasive design and digital health tools in behavioral intervention for chronic diseases, and to discuss the prospects of related health promotion services in improving population health. Method/Process Literature search is conducted by using the Keywords of persuasive design, chronic disease, and behavior intervention. The retrieved literatures are analyzed through narrative review. Result/Conclusion Persuasive design has a good application prospect in chronic disease management and behavioral intervention. Persuasive design should be guided by the principles of providing support for primary tasks, offering interactive feedback, ensuring system authority and credibility, and providing social support.