Purpose/Significance To measure the clinical cost of artificial intelligence aided diagnosis technology for coronary computed tomography angiography (AI-CCTA), and to carry out technical application and operation analysis in sample institutions. Method/Process Activity-based costing is used to estimate and analyze the cost of coronary computed tomography angiography (CCTA) and AI-CCTA, and the operations of the technology is analyzed by cost-volume-profit analysis. Result/Conclusion AI-CCTA can save valuable human resources of diagnostic doctors, improve work efficiency and reduce the cost, and it has certain advantages in clinical application. With the expansion of AI application, the economic operation of medical institutions can be improved.