Purpose/Significance To strengthen the management of scientific and technical novelty search of traditional Chinese medicine (TCM), and to standardize the work of novelty search. Method/Process The process of “Specification for Scientific and Technical Novelty Search of Traditional Chinese Medicine” standard formulation is expounded in detail, and the key points of the standard and its application in science and technology novelty management system are analyzed. Result/Conclusion The standard can better guide the scientific and technical novelty search institutions, standardize the writing of scientific and technical novelty search reports, improve the quality of scientific and technical novelty search reports, and help promote the healthy development of scientific and technical novelty search of TCM. The scientific and technical novelty management system based on the standard improves the efficiency of novelty search.