Purpose/Significance To explore the influence of technology readiness on electronic participation behavior of patients in internet environment. Method/Process The data are collected through the questionnaire survey and analyzed by using propensity score matching method. Result/Conclusion Technology readiness can significantly promote patients’ electronic participation behavior. In the development of internet healthcare, attention should be paid to patients’ technology readiness. By improving patients’ optimism, patients’ discomfort and insecurity about technology should be reduced, and patients should be encouraged to actively use internet technology to participate in their own diagnosis and treatment process.