Purpose/Significance In order to coordinate and promote the high-quality development of hospitals, medical consumables refined supply processing distribution (SPD) based on operational data repository (ODR) is built. Through ODR, cross-departmental data collaboration is realized, and an intelligent operation management system for medical consumables is established. Method/Process Through informatization design and application scenario analysis, the intelligent operation management architecture and service mode of consumables are constructed with data governance as the starting point.Result/Conclusion The intelligent operation system of medical consumables based on ODR will consolidate the fine management results under the SPD mode, strengthen hospital risk control, and further improve the scientific and standardized level of hospital operation and management.