Purpose/Significance To explore and forecast the application prospect of internet in the establishment and improvement of tumor diagnosis and treatment system.Method/Process Based on literature review and field survey, the paper discusses the application prospect from five dimensions:early screening, chronic disease management, evidence-based multi-disciplinary treatment (MDT), tumor rehabilitation and tumor auxiliary diagnosis and treatment platform construction.Result/Conclusion The internet diagnosis and treatment mode can benefit the patients in the aspects of early prevention, early diagnosis and early treatment of tumor. “All-round and all-cycle” health management, out-of-hospital follow-up and education can effectively prolong the survival time of tumor patients and improve their quality of life.