Purpose/Significance To explore the data model design and intelligent applications of health portrait. Method/Process The paper analyzes the current situation and problems of health portrait applications, standardizes the data collection, legislation and governance of health portrait,systematically establishes the data model of health portrait, and explores potential application scenarios for health portrait. Result/Conclusion The data model of health portrait is designed to enhance the comprehensiveness and pertinence of health portrait. The data model management system is established to improve the standardized management efficiency of the model. Two application scenarios of health portrait are summarized,namely “health management and assessment” and “accurate diagnosis and personalized diagnosis and treatment”, which help to improve the quality and effect of medical treatment,and meet individual health needs.