Purpose/Significance Based on the digital health community reference architecture, the technical framework for smart and healthy city is constructed to support the research and development of smart and healthy city. Method/Processs According to the architecture, combined with the needs and practices of the digitalization of the health industry, the “1+1+3+N” technical framework representing the digital infrastructure and smart hub of the smart and healthy city is derived, namely, the one network, unified digital health foundation, three service platforms and N intelligent applications, application analysis is conducted. Result/Conclusion The framework can be used to crack the information interoperability problem, significantly release the value of medical and health data, and support industry users and industry partners to hammer out scenario-based solutions for different business areas, and provide references for the top-level planning, construction and development of smart and healthy cities around the country.