Purpose/Significance To sort out the development history, existing problems and countermeasures of public health informatization, and to provide decision-making reference for informatization construction and improvement of informatization system in domestic public health field. Method/Process Based on the literature related to the research of public health informatization in China in CNKI, the development history and problems of public health informatization are analyzed. Result/Conclusion Public health informatization in China has gone through 4 major stages of development:national co-ordination, key promotion, hierarchical pilot, and interconnection, and there are problems in the infrastructure of disease control informatization, infectious disease informatization construction, information standard system construction, and information security construction, which need to be addressed by countermeasures.