Purpose/Significance To achieve safe and efficient open sharing of health and medical data, and to stimulate the value of health and medical data elements. Method/Process Aiming at the current situation and problems of open sharing of health and medical data, an open sharing system of health and medical data is designed based on data integration governance, data asset management, data product supermarket, data sampling analysis and online sandbox analysis. Result/Conclusion The practice has proved that the system can effectively realize the collection, analysis, management and utilization of health and medical data.