Purpose/Significance The processing links and key technologies of health care big data are deeply discussed to provide information support and guarantee for further promoting the application of health care big data. Method/Process According to the scientific research paradigm driven by big data, and based on the process perspective, the paper introduces the sources and characteristics of health care big data, analyzes the processing links and key technologies of big data, and discusses the current challenges and future development directions of health care big data processing. Result/Conclusion Both China and foreign countries have achieved innovative development in technologies for health care big data processing. However, there are still some challenges in multi-dimensional data collection, multi-modal data integration, large model data analysis, and data security. In the future, through building a comprehensive platform of big data processing, and developing or integrating targeted functional modules, the existing problems can be effectively addressed.