Purpose/Significance To improve data governance level, ensure data security, and achieve standardized management of data resources.Method/Process Practical experience of data classification and grading work in the Chinese Center for Disease Control and Prevention is summarized, goals and significance, implementation process, results and existing problems of data classification and grading management are analyzed.Result/Conclusion The implementation of data classification and grading not only elevates the standardization level of data management, but also provides strong support for ensuring the security of public health data, promoting cross departmental collaboration and information sharing.