Purpose/Significance To investigate and evaluate the realization of core indicators of the provincial coordinated regional infectious disease surveillance, early warning and emergency command information platform constructed by centers for disease control and prevention(CDCs) in 31 provinces (autonomous regions, municipalities directly under the central government) and Xinjiang Production and Construction Corps from 2023 to 2024, and to provide references for the continuous construction and improvement of the platform. Method/Process Evaluation indicators are set based on key tasks, and the completion status data are collected through questionnaires. Result/Conclusion There are regional differences in the progress of the construction and improvement of the provincial coordinated regional infectious disease surveillance, early warning and emergency command information platform. All provincial CDCs should recognize their weaknesses, enhance communication, innovate applications, and strengthen management to promote the high-quality development of infectious disease surveillance, early warning and emergency command through digitalization and intelligence.