Purpose/Significance To investigate the current situation of intelligent management construction in tertiary medical institutions in Guangdong province, so as to enhance the level of intelligent management construction in medical institutions. Method/Process The tertiary medical institutions in Guangdong province are investigated using the online questionnaire survey method, and the data are statistically analyzed by Python, Microsoft Excel and SPSS. Result/Conclusion A total of 203 tertiary medical institutions participate in the research, covering the Pearl River Delta, eastern region, western region and mountainous areas of Guangdong province. The construction status of some intelligent management items of tertiary medical institutions in Guangdong province is relatively good, but the construction level of some projects is still relatively low. Policy guidance should be strengthened, resource input should be increased, and high level talent teams should be formed.