Purpose/Significance To build a technical architecture and application scenario system for smart hospitals, and to form a replicable and implementable paradigm for the construction of smart hospitals. Method/Process The current situation and informatization challenges faced by the construction of smart hospitals are systematically analyzed, and the “cloud-data-intelligence” technical architecture of smart hospitals is proposed. A smart hospital application scenario system covering smart clinical practice, smart services and smart management is constructed and its effectiveness is verified through practice. Result/Conclusion The technical architecture and application scenario system of smart hospitals effectively enhance the work efficiency of medical staffs, the service experience of patients, and the quality of medical services, providing a referrible mode for the construction of smart hospitals for medical institutions.