Purpose/Significance To discuss the opportunities and challenges brought by DeepSeek to the reform of computer courses in medical universities and colleges, and to provide references for improving teaching quality and cultivating high-quality talents in the integration of medicine and engineering. Method/Process The current status of computer course teaching in medical universities and colleges is analyzed. The application approaches of DeepSeek in teaching links are systematically expounded. The challenges faced in the implementation process are discussed, and targeted recommendations and suggestions are proposed. Result/Conclusion DeepSeek can help integrate teaching resources, enhance teaching interactivity and personalization, and improve the teaching evaluation system. However, there are issues such as technical limitations, high hardware requirements, data security risks, and difficulties in personnel adaptation in its application. By avoiding technical limitations, upgrading hardware facilities, strengthening data security safeguards, and conducting personnel training, it is expected to promote the effective reform of computer courses in medical universities and colleges and enhance teaching effectiveness.