我国医学随机对照试验偏倚风险一致性评估
作者:
作者单位:

(1.华东师范大学经济与管理学院信息管理系 上海200062;2.华东师范大学统计与数据科学前沿理论及应用教育部重点实验室 上海 200062)

作者简介:

汤文婷,硕士研究生;通信作者:楼雯,博士,副教授,博士生导师。

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中图分类号:

R-058

基金项目:

教育部重点实验室自主科研项目(项目编号:KLATASDS2406);上海市哲学社会科学项目(项目编号:2024BJC005)。


Assessment of Consistency in the Risk of Bias in Medical Randomized Controlled Trials in China
Author:
Affiliation:

(1.Department of Information Management, School of Economics and Management, East China Normal University, Shanghai 200062, China;2.Key Laboratory of Advanced Theory and Application in Statistics and Data Science (East China Normal University), Ministry of Education of China, Shanghai 200062, China)

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    摘要:

    目的/意义 为临床研究和元分析提供更科学统一的评估标准,提高医学证据质量。方法/过程 检索中国知网,筛选出390条重复的偏倚风险评估记录。对其从整体结果一致性、专题和内容一致性、指标一致性3方面进行分析。结果/结论 超过80%的组别对于同一随机对照试验的风险评估不一致。在主题内容方面,感染性疾病及传染病、内分泌腺及全身性疾病领域研究一致性较高;中医学的Kappa系数分布较广,风险评估一致性差异较大。在指标方面,选择性报道、结果数据的完整性和其他偏倚分歧较大。

    Abstract:

    Purpose/Significance To provide more scientific and unified assessment standards for clinical research and meta-analysis, in order to improve the quality of medical evidence.Method/Process 390 duplicate records of bias risk assessment are retrieved and screened out from CNKI. These records are analyzed from three aspects:overall result consistency, thematic and content consistency, and indicator consistency.Result/Conclusion Over 80% of the groups have inconsistent risk assessments for the same randomized controlled trial. In terms of subject content, there is a high consistency in research on contagious diseases and infectious diseases, endocrine glands and systemic diseases.The Kappa coefficient of traditional Chinese medicine is widely distributed, and there are significant differences in the consistency of risk assessment. In terms of indicators, there are significant differences in selective reporting, completeness of outcome data, and other biases.

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汤文婷,楼雯,刘彦希.我国医学随机对照试验偏倚风险一致性评估[J].医学信息学杂志,2025,46(8):37-44

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  • 最后修改日期:2025-04-22
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  • 在线发布日期: 2025-09-16
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