Purpose/Significance To construct a medical insurance operation management system based on transaction log change data capture (CDC), so as to meet the needs of medical institutions in medical insurance operation management and improve operational efficiency. Method/Process The clinical and management data of the hospital are aggregated, based on transaction log of the business system database, CDC technology is used for data synchronizition, and a medical insurance operation management dataset is further formed. The data is standardized and structured for storage. The medical insurance operation management system is built, enabling personalized customization of medical insurance operation indicators. Result/Conclusion The system achieves the integration and unification of medical insurance data, reduces the operating costs of hospitals, improves the efficiency and quality of medical insurance management, and provides data support for medical insurance decision-making of medical institutions.