Purpose/Significance To uncover the potential health needs of patient groups with rare diseases represented by hemophilia, and to provide references for formulating more precise and effective rare disease support and guarantee measures. Method/Process Using the post texts from Baidu’s “Hemophilia Bar” as the data source, the hot topics of users’ concern and their emotional tendencies are analyzed. Result/Conclusion A total of 9 765 valid post texts are obtained, and seven key themes of concern to hemophilia patients are identified.The attitudes of netizens towards hemophilia-related issues are not optimistic. It is recommended to strengthen the construction of diagnosis and treatment capabilities, establish a multi-dimensional social support network, continuously improve the medical insurance system, and enhance medication management.