Purpose/Significance To establish a “three rings and four chains” double-qualified teacher collaborative training system for masters of medical library and information science, and to promote in-depth integration of industry and education. Method/Process Based on the concept of “all-staff, all-process and all-round education” and employment-oriented education, the practical predicament of the dual-teacher training for masters of medical library and information science is analyzed. Focusing on the three key links of course experiments, internships and practical training, graduation and career selection, as well as the education chain, talent chain, industrial chain and innovation chain, a collaborative training framework of “three rings and four chains” is constructed, and specific implementation paths for the seamless integration of the “three rings” and the deep integration of the “four chains” are proposed. Result/Conclusion Through strategies such as optimizing training objectives, establishing a dual-teacher collaborative training system, integrating practical teaching resources, innovating evaluation and incentive mechanisms, this framework effectively promotes collaborative cooperation between dual-teachers and multi-party collaboration among industry, academia, research, medicine and practice. It provides practical guidance for the innovation of dual-teacher collaborative training models and educational reforms in master’s degree in medical library and information science.