Purpose/Significance To explore the future development trends of medical education driven by the dual wheel of “knowledge graph+large model”, and to provide reference for technological and methodological innovation in this field. Method/Process The application progress of large model in medical education is systematically sorted out, their advantages and limitations are discussed, the development trends of medical education driven by knowledge graph and large model are analyzed. Result/Conclusion The deep integration of knowledge graph and large model will drive innovation and transformation the field of medical education. In the future, it is expected to lead the new trends in the development of medical education aspects such as the development of multimodal teaching resources, the construction of dynamic knowledge bases, and the establishment of intelligent teaching and research systems based on human-machine collaboration.