Purpose/Significance To develop guidelines for the comprehensive evaluation of the clinical application of multi-source cardiopulmonary function evaluation and rehabilitation technology, so as to ensure medical quality and patient safety, and promote the standardized application of the technologies. Method/Process Through systematic basic research, the core framework of the guidelines is established. An interdisciplinary expert team is organized to carry out research through thematic discussions and consensus-building. Result/Conclusion Technical guidance principles, methods, indicators and procedures for the comprehensive evaluation of the clinical application of multi-source cardiopulmonary function assessment and rehabilitation technologies are formulated, forming an index system and guidelines for the comprehensive evaluation of the clinical application of such technology.