Purpose/Significance To discuss the impact of dimensionless methods on the comprehensive scientific and technological evaluation of hospitals, and to provide references for selecting appropriate data processing methods for related research.Method/Process The index data is obtained from the top 100 hospitals listed in the 2022 Annual Report on Chinese Hospitals’ Science and Technology Evaluation Metrics. Methods such as Z-score standardization, range normalization, centralization, interval normalization, and mean normalization are used for data preprocessing. The evaluation results of five dimensionless methods are compared through weighted calculation. Result/Conclusion The results of the range and interval methods are completely positively linearly correlated, while the results of the centralization method have slightly lower correlation with other methods, and there are also significant differences in ranking. The methods of range, interval, Z-score standardization, and mean are applicable to the study of hospitals’ science and technology evaluation metrics.The most appropriate method can be selected based on the evaluation purpose and the data situation.